PNU-159682
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 202350-68-3 | Cat. No. | BCP13117 |
| Name | PNU-159682 | ||
| Synonyms | PNU159682;PNU 159682; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C32H35NO13 | M. Wt | 641.62 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | in vitro: The cytotoxicity of PNU-159682 were in the subnanomolar range (0.07-0.58 nmol/L) and noticeably lower than that recorded for both MMDX and doxorubicin; PNU-159682 was 2,360- to 790-fold and 6,420- to 2,100-fold more potent than MMDX and doxorubicin, respectively . in vivo: An evaluation of the in vivo antitumor activity of PNU-159682, in comparison with that of MMDX, was then conducted in mice bearing disseminated murine L1210 leukemia. Preliminary toxicity dose-finding studies showed that 15 Ag/kg i.v. was the single-dose maximum tolerated dose of PNU-159682 [1]. Several patents reported that PNU-159682 can be used as cytotoxin in ADCs design. | ||
Recommend Products
More >
-
Boc-NH-PEG(3)-COOH
Cat. No.：BCP49651
No.：876345-13-0
Product Details -
-
-
Bis-PEG1-NHSester
Cat. No.：BCP48565
No.：65869-64-9
Product Details -
-
-
-
Boc-Val-Ala-PAB-PNP
Cat. No.：BCP46233
No.：1884578-00-0
Product Details -
Mc-Val-Ala-PAB-PNP
Cat. No.：BCP45729
No.：1639939-40-4
Product Details -
-
Mal-PEG4-VA-PBD
Cat. No.：BCP45309
No.：1342820-68-1
Product Details -
BS3 Crosslinker
Cat. No.：BCP45143
No.：82436-77-9
Product Details -
Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc
Cat. No.：BCP45088
No.：894096-02-7
Product Details -
Mal-PEG2-VCP-Eribulin
Cat. No.：BCP44665
No.：2130869-18-8
Product Details -
Di(N-succinimidyl) glutarate
Cat. No.：BCP44474
No.：79642-50-5
Product Details -
Fmoc-Gly-Gly-Phe-OtBu
Cat. No.：BCP44289
No.：236426-37-2
Product Details -
TCO-PEG4-NHS Ester
Cat. No.：BCP43729
No.：1621096-79-4
Product Details -
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
Cat. No.：BCP36301
No.：1599440-25-1
Product Details -
6-Azido-Hexylamine
Cat. No.：BCP25831
No.：349553-73-7
Product Details -
Tags:PNU-159682 supplier,PNU-159682 purchase,PNU-159682 manufacturer,PNU-159682 distributor,PNU-159682 cost,PNU-159682 buy,PNU-159682 for sale