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WM-1119 Chemical Structure

WM-1119

Data Sheet For research use only. Not for human use.
Cat. No. :BCP29433CAS No. :2055397-28-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2055397-28-7 Cat. No. BCP29433
Name WM-1119
Synonyms MOZ-IN-1; WM 1119; WM1119;
SMILES O=C(NNS(=O)(C1=CC=CC=C1F)=O)C2=CC(C3=NC=CC=C3)=CC(F)=C2
Chemical Name
Formula C18H13F2N3O3S M. Wt 389.38
Purity 98% Storage Store at 4-8°C
Description WM-1119 is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with Kd of 2 nM, WM-1119 is a reversible competitor of acetyl coenzyme A and inhibits MYST-catalysed histone acetylation. WM-1119 induces cell cycle exit and cellular senescence without causing DNA damage. WM-1119 arrests the progression of lymphoma in mice.
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