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Compstatin Chemical Structure

Compstatin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP25108CAS No. :206645-99-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 206645-99-0 Cat. No. BCP25108
Name Compstatin
Synonyms H-Ile-Cys(1)-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-Cys(1)-Thr-NH2;ICVVQDWGHHRCT;
SMILES
Chemical Name
Formula C66H99N23O17S2 M. Wt 1550.78
Purity 98% Storage Store at 4-8°C
Description Compstatinis is a 13-residue cyclic peptide, binds to complement component C3 and inhibits complement activation with IC50 of 12 μM. Compstatin features a high selectivity for human and primate C3. Compstatin completely inhibits in vivo heparin/protamine-induced complement activation without adverse effects on heart rate or systemic arterial, central venous, and pulmonary arterial pressures.
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