Gemcitabine elaidate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 210829-30-4 | Cat. No. | BCP07317 |
| Name | Gemcitabine elaidate | ||
| Synonyms | CO-101; CP-4126; CO 101; CP 4126; CO101; CP4126; Gemcitabine 5'-elaidate; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C27H43F2N3O5 | M. Wt | 527.64 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Gemcitabine elaidate (also known as CO-101; CP-4126) is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide po | ||
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