Purvalanol A
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 212844-53-6 | Cat. No. | BCP06309 |
| Name | Purvalanol A | ||
| Synonyms | NG 60;NG-60;NG60;Purvalanol-A; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C19H25ClN6O | M. Wt | 388.89 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Purvalanol A is a potent CDK inhibitor, which effectively suppresses Src-mediated transformation by inhibiting both CDKs and c-Src. indicating that the activation of CDKs contributes to the c-Src transformation. Purvalanol A suppressed the c-Src activity as effectively as the Src-selective inhibitor PP2, and that it reverted the transformed morphology to a nearly normal shape with less cytotoxicity than PP2. Purvalanol A induced a strong G2-M arrest, whereas PP2 weakly acted on the G1-S transition. Furthermore, when compared with PP2, purvalanol A more effectively suppressed the growth of human colon cancer HT29 and SW480 cells, in which Src family kinases and CDKs are activated. | ||
Recommend Products
More >
-
6-Hydroxystigmast-4-en-3-one
Cat. No.：BCP29055
No.：36450-02-9
Product Details -
3-Trifluormethyl-furan
Cat. No.：BCP29053
No.：56286-84-1
Product Details -
Trans-5-(Benzyloxyamino)piperidine-2-carboxylic acid,sodium salt
Cat. No.：BCP29007
No.：2122800-38-6
Product Details -
-
(1R,5S)-3-ethyl-Bicyclo[3.2.0]hept-3-en-6-one
Cat. No.：BCP29004
No.：1235479-61-4
Product Details -
6-Chloro-5-methylpyridazin-3-amine
Cat. No.：BCP28935
No.：66346-87-0
Product Details -
4-Acetyl-3-hydroxypyridine
Cat. No.：BCP28934
No.：30152-05-7
Product Details -
cis-Aconitic Anhydride
Cat. No.：BCP28868
No.：6318-55-4
Product Details -
2,2,6-Trimethyl-4H-1,3-dioxin-4-one
Cat. No.：BCP28867
No.：5394-63-8
Product Details -
(R)-tert-Butyl 3-bromopiperidine-1-carboxylate
Cat. No.：BCP28864
No.：1354000-03-5
Product Details -
tert-Butyl 8-amino-2-azaspiro[4.5]decane-2-carboxylate
Cat. No.：BCP28871
No.：1363381-61-6
Product Details -
1H-Isoindole-1,3(2H)-dione, 2-(3-oxocyclopentyl)-
Cat. No.：BCP28872
No.：1029691-06-2
Product Details -
tert-Butyl (1R,3S,4S)-3-(6-(7-(2-((S)-5-(tert-butoxycarbonyl)-5-azaspiro(2.4)heptan-6-yl)-1H-imidazol-5-yl)-9,9-difluoro-9H-fluoren-2-yl)-1H-benzo(d)i
Cat. No.：BCP28873
No.：1499193-66-6
Product Details -
quinazolin-4-ol
Cat. No.：BCP00749
No.：491-36-1
Product Details -
tert-butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate
Cat. No.：BCP00820
No.：923009-50-1
Product Details -
benzyl 3-oxopiperazine-1-carboxylate
Cat. No.：BCP03381
No.：78818-15-2
Product Details -
Methyl 3-bromopyrazine-2-carboxylate
Cat. No.：BCP03415
No.：51171-02-9
Product Details -
-
Benzyl butanedioic acid anhydride
Cat. No.：BCP08177
No.：19544-43-5
Product Details -
1,3-DI-BOC-2-(TRIFLUOROMETHYLSULFONYL)GUANIDINE
Cat. No.：BCP08347
No.：207857-15-6
Product Details
Tags:Purvalanol A supplier,Purvalanol A purchase,Purvalanol A manufacturer,Purvalanol A distributor,Purvalanol A cost,Purvalanol A buy,Purvalanol A for sale