Purvalanol B
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CAS No. | 212844-54-7 | Cat. No. | BCP01952 |
Name | Purvalanol B | ||
Synonyms | NG 95;NG95;NG-95; | ||
SMILES | O=C(O)C1=CC=C(NC2=C3N=CN(C(C)C)C3=NC(N[C@@H](CO)C(C)C)=N2)C=C1Cl | ||
Chemical Name | |||
Formula | C20H25ClN6O3 | M. Wt | 432.9 |
Purity | 97% | Storage | Store at 4-8°C |
Description | Purvalanol B, also known as NG 95, is a potent and selective CDK inhibitor that most potently inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively). |
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