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CU-CPT-9b Chemical Structure

CU-CPT-9b

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP29122CAS No. ：2165340-32-7Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 2165340-32-7 Cat. No. BCP29122
Name CU-CPT-9b
Synonyms CU-CPT-9B; CPD2004;CU-CPT9b;
SMILES
Chemical Name
Formula C17H15NO2 M. Wt 265.31
Purity 98% Storage Store at 4-8°C
Description CU-CPT-9B is a potent, selective TLR8 inhibitor with IC50 of 0.7 nM, Kd of 21 nM, and negligible cytotoxicity; shows no significant inhibition for other TLRs at 1 uM in cellular assays; consistently recognizes an allosteric pocket on the protein-protein interface, stabilizing the inactive TLR8 dimer.
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