Fludarabine New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 21679-14-1 | Cat. No. | BCP01383 |
| Name | Fludarabine | ||
| Synonyms | Fludara;HSDB 6964; HSDB6964; HSDB-6964; NSC 118218; NSC118218; NSC-118218; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C10H12FN5O4 | M. Wt | 285.23 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Fludarabine efficiently inhibits the proliferation of RPMI 8226 cells with IC50 of 1.54 μg/mL. The IC50 of Fludarabine against MM.1S and MM.1R cells is 13.48 μg/mL and 33.79 μg/mL, respectively. In contrast, U266 cells are resistant to Fludarabine with IC50 of 222.2 μg/mL. Fludarabine treatment results in increased number of cells in the G1 phase of cell cycle, accompanied with a concomitant reduction of cells at the S phase of cell cycle in a time-dependent manner. Fludarabine induces a cell cyc | ||
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