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Ixabepilone Chemical Structure

Ixabepilone

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP07847CAS No. ：219989-84-1Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 219989-84-1 Cat. No. BCP07847
Name Ixabepilone
Synonyms Azaepothilone B;BMS247550;BMS-247550;Ixempra;BMS 247550;; BMS 247550-1;BMS-247550-1;BMS247550-1;
SMILES CC1CCCC2(C(O2)CC(NC(=O)CC(C(C(=O)C(C1O)C)(C)C)O)C(=CC3=CSC(=N3)C)C)C
Chemical Name
Formula C27H42N2O5S M. Wt 506.7
Purity 98% Storage Store at 4-8°C
Description Ixabepilone is an orally bioavailable semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane-resistant cell lines.
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H-NMR
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