Talaporfin Sodium New
Data Sheet
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| CAS No. | 220201-34-3 | Cat. No. | BCP16109 |
| Name | Talaporfin Sodium | ||
| Synonyms | LS11; LS-11; LS 11; ME2906;ME 2906; ME-2906;NPe6; | ||
| SMILES | CCC1=C2C=C3C(=C(C(=N3)C(=C4C(C(C(=N4)C=C5C(=C(C(=CC(=C1C)N2)N5)C=C)C)C)CCC(=O)[O-])CC(=O)NC(CC(=O)[O-])C(=O)[O-])C(=O)[O-])C.[Na+].[Na+].[Na+].[Na+] | ||
| Chemical Name | |||
| Formula | C38H37N5O9.4Na | M. Wt | 799.7 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Talaporfin sodium is a natural chlorophyll-based, and water soluble PDT photosensitizer consisting of chlorin e6, derived from chlorophyll, and L-aspartic acid with photosensitizing activity. After intratumoral activation by light emitting diodes, talaporfin sodium forms an extended high energy conformational state that generates singlet oxygen, which can kill target tissues with minimal side effects through vascular closure and apoptosis. Constant illumination can activate each molecule of talaporfin many times, resulting in a continuous supply of singlet oxygen molecules. Talaporfin kills all tumour cells in the targeted zone, rather than only the minority of cells undergoing rapid division, as in the case of chemotherapy. | ||
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