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CAS No. | 223499-30-7 | Cat. No. | BCP19298 |
Name | YM-58483 | ||
Synonyms | BTP2;YM 58483;YM58483;CRAC Channel Inhibitor, BTP2;BTP-2;BTP 2; | ||
SMILES | CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F | ||
Chemical Name | |||
Formula | C15H9F6N5OS | M. Wt | 421.32 |
Purity | 98% | Storage | Store at 4-8°C |
Description | YM-58483 is a calcium release-activated calcium (CRAC) channel inhibitor. YM 58483 suppresses thapsigargin-induced sustained Ca2+ influx (IC50 = 100 nM), cytokine production and proliferation of T cells in vitro. YM 58483 exhibits immuno-modulatory and anti-inflammatory activity. |
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