Toll-Like Receptor 7 Ligand II
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CAS No. | 226907-52-4 | Cat. No. | BCP26295 |
Name | Toll-Like Receptor 7 Ligand II | ||
Synonyms | SM360320; SM-360320; SM 360320; CL-087; CL 087; CL087; 1V136; | ||
SMILES | |||
Chemical Name | |||
Formula | C15H17N5O3 | M. Wt | 315.33 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Toll-Like Receptor 7 Ligand II , also known as CL-087 or SM360320, is a potent, orally active and selective TLR7 agonist. SM360320 induced in vivo secretion of interferon alpha (IFNalpha) and exerted a significant antitumor effect in CEA.Tg mice challenged with a syngenic tumor cell line expressing CEA and an additive effect with a CEA vaccine. SM360320 may have potential as immunological adjuvant for therapeutic DNA vaccines. |
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