Probucol
Data Sheet
For research use only. Not for human use.
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| CAS No. | 23288-49-5 | Cat. No. | BCP06487 |
| Name | Probucol | ||
| Synonyms | Lorelco; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C31H48O2S2 | M. Wt | 516.84 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Probucol is a drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. Probucol inhibited cholesterol efflux up to 80% in J774 macrophages expressing ABCA1. probucol is an effective inhibitor of ABCA1-mediated cholesterol efflux without influencing scavenger receptor class B type I-mediated efflux. The inhibition of ABCA1 translocation to the plasma membrane may in part explain the reported in vivo high-density lipoprotein-lowering action of probucol . | ||
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