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Droxidopa Chemical Structure

Droxidopa

Data Sheet For research use only. Not for human use.
Cat. No. :BCP06516CAS No. :23651-95-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 23651-95-8 Cat. No. BCP06516
Name Droxidopa
Synonyms SM 5688;SM-5688;SM5688;
SMILES
Chemical Name
Formula C9H11NO5 M. Wt 213.19
Purity 98% Storage Store at 4-8°C
Description Droxidopa is a pro-drug which has a structure similar to noradrenaline, but with a carboxyl group. Droxidopa can be administered orally, unlike noradrenaline, and after absorption is converted by the enzyme dopa decarboxylase into noradrenaline thus increasing levels of the neurotransmitter which is identical to endogenous noradrenaline.Droxidopa is well tolerated.Droxidopa could exert its pressor effect in three different ways: a) as a central stimulator of sympathetic activity; b) as a peripheral sympathetic neurotransmitter; c) as a circulating hormone. Droxidopa taken alone increases standing blood pressure. Droxidopa can also cross the blood–brain barrier (BBB) where it is converted to norepinephrine and epinephrine from within the brain.
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