JHU37160 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2369979-68-8 | Cat. No. | BCP40726 |
| Name | JHU37160 | ||
| Synonyms | JHU-37160;JHU 37160; | ||
| SMILES | CCN1CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=C2C=CC=C4F | ||
| Chemical Name | |||
| Formula | C19H20ClFN4 | M. Wt | 358.8 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | JHU37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively. | ||
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