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Mobocertinib succinate Chemical Structure

Mobocertinib succinate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP33315CAS No. :2389149-74-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2389149-74-8 Cat. No. BCP33315
Name Mobocertinib succinate
Synonyms TAK-788 succinate; AP32788 succinate;TAK 788 succinate; AP 32788 succinate;TAK788 succinate; AP-32788 succinate;
SMILES O=C(C1=CN=C(NC2=CC(NC(C=C)=O)=C(N(CCN(C)C)C)C=C2OC)N=C1C3=CN(C)C4=C3C=CC=C4)OC(C)C.O=C(O)CCC(O)=O
Chemical Name
Formula C36H45N7O8 M. Wt 703.78
Purity 98% Storage Store at 4-8°C
Description Mobocertinib succinate is a potent and orally active inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, with selectivity over WT EGFR. Antitumor activity.Mobocertinib, also known as TAK-788 and AP32788, is an investigational TKI with potent, selective preclinical activity against activating EGFR and HER2 mutations, including exon 20 insertions. TAK-788 exhibits antitumor activity in pts with EGFR exon 20 insertions with an AE profile consistent with other EGFR TKIs.
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