Catharanthine
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2468-21-5 | Cat. No. | BCP07491 |
| Name | Catharanthine | ||
| Synonyms | |||
| SMILES | |||
| Chemical Name | |||
| Formula | C21H24N2O2 | M. Wt | 336.43 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Catharanthine is a precursor of the anti-tumor drugs vinblastine and vincristine, formed by dimerization of catharanthine with vindoline. Catharanthine itself is an inhibitor of tubulin self-assembly into microtubules, although not so potent as vinblastine or vincristine. Catharanthine also has anticholinergic activity. It showed muscarinic antagonism at 10 microM and fully inhibited nicotinic receptor mediated diaphragm contractions with an IC50 of 59.6 microM. | ||
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