Polyinosinic-polycytidylic acid New
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For research use only. Not for human use.
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| CAS No. | 24939-03-5 | Cat. No. | BCP14941 |
| Name | Polyinosinic-polycytidylic acid | ||
| Synonyms | Poly I-C; Poly(I+C);Polyinosinic Polycytidylic Acid;Poly I:C; | ||
| SMILES | C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O | ||
| Chemical Name | |||
| Formula | C19H27N7O16P2 | M. Wt | 671.4 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed in the membrane of B-cells, macrophages and dendritic cells. Poly I:C is structurally similar to double-stranded RNA, which is present in some viruses and is a "natural" stimulant of TLR3. Thus, Poly I:C can be considered a synthetic analog of double-stranded RNA and is a common tool for scientific research on the immune system | ||
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