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Orantinib Chemical Structure

Orantinib

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP01984CAS No. ：252916-29-3Purity：98%
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  • Publications Citing of Biochempartner's Orantinib
Neoplasia. 2019 Apr; 21(4): 389–400.
  • Chemical Properties&Biological Activity
CAS No. 252916-29-3 Cat. No. BCP01984
Name Orantinib
Synonyms TSU68; TSU 68; TSU-68; SU6668; SU 6668; SU-6668;
SMILES O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=CC=C3)=O)=C1C
Chemical Name
Formula C18H18N2O3 M. Wt 310.35
Purity 98% Storage Store at 4-8°C
Description Orantinib, also known as TSU-68；SU6668, is an orally bioavailable receptor tyrosine kinase inhibitor. Orantinib binds to and inhibits the autophosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), and fibroblast growth factor receptor (FGFR), thereby inhibiting angiogenesis and cell proliferation. Orantinib also inhibits the phosphorylation of the stem cell factor receptor tyrosine kinase c-kit, often expressed in acute myelogenous leukemia cells. Check for active clinical trials or closed clinical trials using this agent.
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LCMS H-NMR
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