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CAS No. | 269390-77-4 | Cat. No. | BCP18097 |
Name | AAL-993 | ||
Synonyms | AAL993;AAL 993;ZK260253; | ||
SMILES | C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NCC3=CC=NC=C3 | ||
Chemical Name | |||
Formula | C20H16F3N3O | M. Wt | 371.36 |
Purity | 98% | Storage | Store at 4-8°C |
Description | AAL-993 is a highly potent inhibitor of VEGFR-1 (IC50 =130nM), VEGFR-2 (IC50=23nM) and VEGFR-3 (IC50=18nM). At higher concentrations it inhibits PDGFR-β (640nM), c-Kit (236nM) and CSF-1R (380nM). |
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