SLV-308 hydrochloride
Data Sheet
For research use only. Not for human use.
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| CAS No. | 269718-83-4 | Cat. No. | BCP17730 |
| Name | SLV-308 hydrochloride | ||
| Synonyms | Pardoprunox hydrochloride;DU-126891 hydrochloride;DU126891 hydrochloride;DU 126891 hydrochloride;SLV-308 hydrochloride;SLV 308 hydrochloride;SLV308 hyd; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C12H16ClN3O2 | M. Wt | 269.73 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Pardoprunox, also known as SLV-308; DU-126891; SME-308, is dopamine D2/5-HT1A receptor agonist potentially for the treatment of Parkinson's disease. It was also being investigated for the treatment of depression and anxiety but these indications appear to have been abandoned. Pardoprunox acts as a D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist (IA = 50% and 67%, respectively) and 5-HT1A receptor (pKi = 8.5) full agonist (IA = 100%). It also binds to D4 (pKi = 7.8), α1-adrenergic (pKi = 7.8), α2-adrenergic (pKi = 7.4), and 5-HT7 receptors (pKi = 7.2) with lower affinity. | ||
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