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Tuspetinib hydrate Chemical Structure

Tuspetinib hydrate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP49212CAS No. :2758339-04-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2758339-04-5 Cat. No. BCP49212
Name Tuspetinib hydrate
Synonyms HM43239 monohydrate;HM-43239 monohydrate;HM 43239 monohydrate;
SMILES
Chemical Name
Formula C29H35ClN6O M. Wt 519.1
Purity 98% Storage Store at 4-8°C
Description Tuspetinib is a selective, reversible type I inhibitor of FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2) with potential antineoplastic activity. Upon administration, tuspetinib reversibly binds to and inhibits the activity of FLT3. This inhibits the proliferation of FLT3-expressing cancer cells. FLT3, a class III receptor tyrosine kinase (RTK), is overexpressed or mutated in most B-lineage neoplasms and in acute myeloid leukemias.
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