SB216763
Data Sheet
For research use only. Not for human use.
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| CAS No. | 280744-09-4 | Cat. No. | BCP01764 |
| Name | SB216763 | ||
| Synonyms | SB-216763;SB 216763; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C19H12Cl2N2O2 | M. Wt | 371.22 |
| Purity | >95% | Storage | Store at 4-8°C |
| Description | SB 216763 is potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 9 nM for GSK-3α); competes with ATP. SB 216763 has minimal activity against 24 other protein kinases (IC50 > 10 μ M). Stimulates glycogen synthesis, gene transcription and is neuroprotective. SB 216763 also reduces pulmonary inflammation and fibrosis in a mouse model. | ||
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