Scriptaid

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP06506CAS No. ：287383-59-9Purity：98%

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CAS No.	287383-59-9	Cat. No.	BCP06506
Name	Scriptaid
Synonyms	GCK 1026;Scriptide;GCK1026;GCK-1026;
SMILES
Chemical Name
Formula	C18H18N2O4	M. Wt	326.35
Purity	98%	Storage	Store at 4-8°C
Description	Scriptaid (6 μM) results in a >100-fold increase in histone acetylation in PANC-1 cell. Scriptaid (8 μM) is not lethal to PANC-1 cell and has limited effects (80% survival) on MDAMB-468. Scriptaid increases the transcription of pCMVb, p6SBE-luc and p6MBE-luc independent of a positive inducer of transcription. Scriptaid is capable of inducing high expression of p6MBE-luc, pCMVb, and pUB6/V5-LacZ, driven by viral (SV40 and CMV) or human (ubiquitin c, UB6) promoters, which do not depend on the specificity of the enhancer (SBE versus MBE), the type of promoter (viral versus cellular), the product of the reporter gene (luciferase versus b-gal), nor on the integration status of the reporter construct.Scriptaid induces high rates of somatic cell nuclear transfer (SCNT) oocytes development to the blastocyst stage and allowed full-term development (3.4, 4.2, 7.6, 6.8, and 4.1%) with all concentrations (50, 100, 250, 500, and 2000 nM respectively). Scriptaid improves the full-term development of