E7820
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CAS No. | 289483-69-8 | Cat. No. | BCP25835 |
Name | E7820 | ||
Synonyms | E-7820; E 7820;ER68203-00; | ||
SMILES | |||
Chemical Name | |||
Formula | C17H12N4O2S | M. Wt | 336.37 |
Purity | 98% | Storage | Store at 4-8°C |
Description | E7820 is a small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis. |
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