SB3CT
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CAS No. | 292605-14-2 | Cat. No. | BCP10428 |
Name | SB3CT | ||
Synonyms | SB-3CT;SB 3CT; | ||
SMILES | |||
Chemical Name | |||
Formula | C15H14O3S2 | M. Wt | 306.4 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. SB-3CT is a 2-[(arylsulfonyl)methyl]thiirane that achieves potent inhibition, by a thiirane-opening mechanism, of the MMP2 and MMP9 zinc metalloproteases. SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat. Matrix metalloproteinases (MMPs) are involved in a number of activities including angiogenesis and embryogenesis. In particular, gelatinases A (MMP-2) and B (MMP-9), are thought to facilitate tumor metastasis. |
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