Dynasore
Data Sheet
For research use only. Not for human use.
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| CAS No. | 304448-55-3 | Cat. No. | BCP07648 |
| Name | Dynasore | ||
| Synonyms | LM-8047; LM8047; | ||
| SMILES | O=C(C1=C(O)C=C2C=CC=CC2=C1)N/N=C/C3=CC=C(O)C(O)=C3 | ||
| Chemical Name | |||
| Formula | C18H14N2O4H2O | M. Wt | 322.31 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Dynasore is a dynamin inhibitor (IC50 = 15 μM). dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts. Dynasore disrupts trafficking of herpes simplex virus proteins. Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation. Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart. Dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages. | ||
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