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Ghrelin Chemical Structure

Ghrelin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP08448CAS No. :304853-26-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 304853-26-7 Cat. No. BCP08448
Name Ghrelin
Synonyms Growth hormone secretagogue;
SMILES
Chemical Name
Formula C149H249N47O42 M. Wt 3370.86
Purity 98% Storage Store at 4-8°C
Description Ghrelin, a 28 aa peptide predominantly produced by the stomach, is an endogenous ligand for the growth hormone secretagogue receptor (GHS-R) that potently stimulates growth hormone release. Studies suggest that peripherally or centrally administrated ghrelin, independent of growth hormone, decreases fat oxidation and increases food intake and adiposity. In addition, plasma ghrelin levels are lower in obese human subjects. Ghrelin promotes the production of orexigenic neuropeptides (neuropeptide Y and agouti-related protein) in the hypothalamic arcuate nuclei and activates the neurons which produce these orexigenic neuropeptides, resulting in an increase in feeding and body weight and thereby opposing the effects of leptin. Moreover, ghrelin shows regulatory effects on the cardiovascular and immune system.
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