SMER28
Data Sheet
For research use only. Not for human use.
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| CAS No. | 307538-42-7 | Cat. No. | BCP17486 |
| Name | SMER28 | ||
| Synonyms | SMER-28;SMER 28; | ||
| SMILES | C=CCNC1=C2C=C(Br)C=CC2=NC=N1 | ||
| Chemical Name | |||
| Formula | C11H10BrN3 | M. Wt | 264.12 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SMER28 is a small molecule modulator of autophagy, inducing autophagy independently of rapamycin in mammalian cells. SMER28, acting via an mTOR-independent mechanism, prevented the accumulation of amyloid beta peptide within these cells. SMER28 may have therapeutic potential for the treatment of Alzheimer's disease and other proteinopathies. | ||
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