Glutaminase C-IN-1
Data Sheet
For research use only. Not for human use.
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| CAS No. | 311795-38-7 | Cat. No. | BCP18024 |
| Name | Glutaminase C-IN-1 | ||
| Synonyms | GLS-IN-968; GLS IN 968; GLSIN968; Glutaminase inhibitor-968; Glutaminase inhibitor 968; GLS inhibitor 968; Glutaminase inhibitor compound 968; | ||
| SMILES | O=C1C(C(C2=CC=C(N(C)C)C(Br)=C2)NC3=C4C5=CC=CC=C5C=C3)=C4CC(C)(C)C1 | ||
| Chemical Name | |||
| Formula | C27H27BrN2O | M. Wt | 475.42 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Glutaminase inhibitor compound is a cell-permeable, reversible inhibitor of a mitochrondrial glutaminase splice variant, glutaminase C (IC50 = ~2.5 μM), which is commonly found in cancer cells.GLS-IN-968 is an allosteric inhibitor of glutaminase (GLS). It acts by blocking Rho-GTPase-dependent transformation of fibroblasts and suppressing breast cancer cell growth and invasive activity in vitro. | ||
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