ICA-121431
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CAS No. | 313254-51-2 | Cat. No. | BCP28611 |
Name | ICA-121431 | ||
Synonyms | ICA 121431; ICA121431; | ||
SMILES | |||
Chemical Name | |||
Formula | C23H19N3O3S2 | M. Wt | 449.55 |
Purity | 97% | Storage | Store at 4-8°C |
Description | ICA-121431 is a potent, selective inhibitor of the human Nav1.3 and Nav1.1 voltage gated sodium channels (IC50 = 19 nM) with little or no activity against human Nav1.5 or Nav1.7 channels. Voltage-gated sodium channels initiate action potentials in brain neurons, and sodium channel blockers are used in therapy of epilepsy. |
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