Rosiglitazone sodium
Data Sheet
For research use only. Not for human use.
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| CAS No. | 316371-83-2 | Cat. No. | BCP28479 |
| Name | Rosiglitazone sodium | ||
| Synonyms | BRL49653; BRL-49653; BRL 49653; HSDB 7555; HSDB-7555; HSDB7555; TDZ 01; TDZ-01; TDZ01; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C18H18N3NaO3S | M. Wt | 379.41 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Rosiglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. It works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Rosiglitazone is a member of the thiazolidinedione class of drugs. Thiazolidinediones act as insulin sensitizers. They reduce glucose, fatty acid, and insulin blood concentrations. They work by binding to the peroxisome proliferator-activated receptors (PPARs). PPARs are transcription factors that reside in the nucleus and become activated by ligands such as thiazolidinediones. Thiazolidinediones enter the cell, bind to the nuclear receptors, and alter the expression of genes. | ||
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