ZM323881
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CAS No. | 324077-30-7 | Cat. No. | BCP06446 |
Name | ZM323881 | ||
Synonyms | ZM-323881;ZM 323881; | ||
SMILES | |||
Chemical Name | |||
Formula | C22H18FN3O2 | M. Wt | 375.4 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ZM323881 selectively inhibits VEGFR-2 (IC50 = 2 nM) over VEGFR-1 and a range of other receptor tyrosine kinases such as PDGFRβ, FGFR1, EGFR and erbB2 (IC50 > 50 μM). ZM323881 inhibits VEGF-A-induced endothelial cell proliferation in vitro (IC50 = 8 nM). |
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