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CAS No. | 327036-89-5 | Cat. No. | BCP07657 |
Name | TDZD-8 | ||
Synonyms | GSK-3β Inhibitor I; NP01139;TDZD8; TDZD 8; NP 01139; NP-01139;GSK-3beta Inhibitor I; | ||
SMILES | |||
Chemical Name | |||
Formula | C10H10N2O2S | M. Wt | 222.26 |
Purity | 98% | Storage | Store at 4-8°C |
Description | TDZD-8 is a selective inhibitor of GSK-3, a thiadiazolidinone derivative, non-ATP competitive inhibitor of GSK-3β (IC50 = 2 μM). It does not inhibit Cdk-1/cyclin B, CK-II, PKA or PKC at >100 μM. TDZD-8 has been proposed to bind to the kinase site of GSK-3β. |
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