Optovin
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CAS No. | 348575-88-2 | Cat. No. | BCP28017 |
Name | Optovin | ||
Synonyms | |||
SMILES | |||
Chemical Name | |||
Formula | C15H13N3OS2 | M. Wt | 315.41 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Optovin is a photoactive TRPA1 activator. Optovin activates human TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues. In animals with severed spinal cords, optovin treatment enables control of motor activity in the paralyzed extremities by localized illumination. These studies identify a light-based strategy for controlling endogenous TRPA1 receptors in vivo, with potential clinical and research applications in nontransgenic animals, including humans. |
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