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GSK137647A
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CAS No. | 349085-82-1 | Cat. No. | BCP17136 |
Name | GSK137647A | ||
Synonyms | GSK-137647A ;GSK 137647A ;GSK 137647;GSK-137647;GSK137647; | ||
SMILES | |||
Chemical Name | |||
Formula | C16H19NO3S | M. Wt | 305.39 |
Purity | 98% | Storage | Store at 4-8°C |
Description | The pEC50s for Human , Mouse and Rat FFA1/2/3 are < 4.5. GSK137647A is evaluated against a panel of 65 targets in both full curve functional and binding assays and was shown to provide at least 100-fold selectivity against the panel which included 41 G-protein-coupled receptors (GPCRs), including additional members of the free fatty acid receptors (FFA1, FFA2, and FFA3). GSK137647A produces a concentration-dependent increase in glucose stimulated insulin secretion under high glucose conditions (25 mM). |
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