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Triciribine Chemical Structure

Triciribine

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP01849CAS No. ：35943-35-2Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 35943-35-2 Cat. No. BCP01849
Name Triciribine
Synonyms API-2; NSC-154020; NSC 154020; NSC154020; TCN;
SMILES
Chemical Name
Formula C13H16N6O4 M. Wt 320.3
Purity 98% Storage Store at 4-8°C
Description Triciribine is a potent AKT inhibitor and a cell-permeable tricyclic nucleoside molecule with potential antineoplastic activity. Triciribine inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation. Akts are anti-apoptotic serine/theronine-specific protein kinases that phosphorylate and inactivate components of the apoptotic machinery, including Bcl-xL/Bcl-2-associated death promoter (BAD) and caspase 9.
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