Dimebon
Data Sheet
For research use only. Not for human use.
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| CAS No. | 3613-73-8 | Cat. No. | BCP02189 |
| Name | Dimebon | ||
| Synonyms | Latrepirdine;Dimebolin; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C21H25N3 | M. Wt | 319.44 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Latrepirdine (INN, also known as dimebolin and sold as Dimebon), is an antihistamine drug. Research is continuing in both Russia and western nations into potential applications as a neuroprotective drug to combat Alzheimer’s disease and, possibly, as a nootropic as well. However, a Phase III clinical trial for Alzheimer’s disease treatment failed to show any benefit. Latrepirdine operates through multiple mechanisms of action, blocking the action of neurotoxic beta-amyloid proteins, inhibiting L-type calcium channels, modulating the action of AMPA and NMDA glutamate receptors, exerting a neuroprotective effect by blocking a novel target that involves mitochondrial pores, blocking a number of other receptors including α-adrenergic, 5-HT2C, 5-HT5A, and 5-HT6. | ||
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