Diazoxide
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CAS No. | 364-98-7 | Cat. No. | BCP26107 |
Name | Diazoxide | ||
Synonyms | Eudemine; Hyperstat; Proglycem; Hypertonalum; Proglicem; | ||
SMILES | |||
Chemical Name | |||
Formula | C8H7ClN2O2S | M. Wt | 230.67 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Diazoxide is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. This switches off voltage-gated calcium ion channels, preventing calcium flux across the sarcolemma and activation of the contractile apparatus. This agent also inhibits insulin release by interacting with ATP-sensitive potassium channels of pancreatic islet beta-cells. |
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