Rivaroxaban
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CAS No. | 366789-02-8 | Cat. No. | BCP00165 |
Name | Rivaroxaban | ||
Synonyms | BAY59-7939; BAY 59-7939; BAY-59-7939;Xarelto; | ||
SMILES | C1COCC(=O)N1C2=CC=C(C=C2)N3CC(OC3=O)CNC(=O)C4=CC=C(S4)Cl | ||
Chemical Name | |||
Formula | C19H18ClN3O5S | M. Wt | 435.88 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Rivaroxaban also inhibits prothrombinase activity with IC50 of 2.1 nM. Rivaroxaban also shows a similar affinity to purified human and rabbit FXa (IC50 0.7 nM and 0.8 nM, respectively), but a lesser potency against purified rat FXa (IC50 3.4 nM). Endogenous human and rabbit FXa in plasma is inhibited to a similar extent by Rivaroxaban (IC50 21 nM and 21 nM, respectively), while 14-fold higher concentrations are required in rat plasma (IC50 290 nM). |
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