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Rivaroxaban Chemical Structure

Rivaroxaban

Data Sheet For research use only. Not for human use.
Cat. No. :BCP00165CAS No. :366789-02-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 366789-02-8 Cat. No. BCP00165
Name Rivaroxaban
Synonyms BAY59-7939; BAY 59-7939; BAY-59-7939;Xarelto;
SMILES C1COCC(=O)N1C2=CC=C(C=C2)N3CC(OC3=O)CNC(=O)C4=CC=C(S4)Cl
Chemical Name
Formula C19H18ClN3O5S M. Wt 435.88
Purity 98% Storage Store at 4-8°C
Description Rivaroxaban also inhibits prothrombinase activity with IC50 of 2.1 nM. Rivaroxaban also shows a similar affinity to purified human and rabbit FXa (IC50 0.7 nM and 0.8 nM, respectively), but a lesser potency against purified rat FXa (IC50 3.4 nM). Endogenous human and rabbit FXa in plasma is inhibited to a similar extent by Rivaroxaban (IC50 21 nM and 21 nM, respectively), while 14-fold higher concentrations are required in rat plasma (IC50 290 nM).
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