SB 612111 HCl
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CAS No. | 371980-98-2 | Cat. No. | BCP27704 |
Name | SB 612111 HCl | ||
Synonyms | SB-612111;SB612111; SB 612111 HCl; SB612111 HCl; | ||
SMILES | |||
Chemical Name | |||
Formula | C24H29Cl2NO.HCl | M. Wt | 454.86 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SB 612111 HCl is a selective NOP receptor antagonist (Ki values are 0.33, 57.6, 160.5 and 2109 nM for NOP, μ-, κ- and δ-receptors respectively). It antagonizes the pronociceptive action of nociceptin (Cat. No. 0910) in an acute pain model. SB 612111 HCl potentiates the action of morphine in morphine-tolerant animals and blocks hyperalgesia in an inflammatory pain model. |
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