BCTC
Data Sheet
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| CAS No. | 393514-24-4 | Cat. No. | BCP19629 |
| Name | BCTC | ||
| Synonyms | |||
| SMILES | |||
| Chemical Name | |||
| Formula | C20H25ClN4O | M. Wt | 372.90 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BCTC is an orally effective vanilloid receptor 1 (TRPV1 receptor) antagonist. Inhibits acid- and capsaicin-induced activation of rat TRPV1 receptors (IC50 values are 6.0 and 35 nM respectively). BCTC significantly reduced the accompanying thermal and mechanical hyperalgesia (3 mg/kg and 10 mg/kg p.o., respectively). BCTC also reduced mechanical hyperalgesia and tactile allodynia 2 weeks after partial sciatic nerve injury (10 and 30 mg/kg p.o.). BCTC did not affect motor performance on the rotarod after administration of doses up to 50 mg/kg | ||
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