Cefamandole formate sodium salt
Data Sheet
For research use only. Not for human use.
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| CAS No. | 42540-40-9 | Cat. No. | BCP10739 |
| Name | Cefamandole formate sodium salt | ||
| Synonyms | Cefamandole Nafate; Cemandil sodium salt; Cefamandol nafato; O-Formylcefamandole sodium; Cephamandole nafate; | ||
| SMILES | CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(C4=CC=CC=C4)OC=O)SC2)C(=O)[O-].[Na+] | ||
| Chemical Name | |||
| Formula | C19H17N6NaO6S2 | M. Wt | 512.5 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Cefamandole Nafate is the sodium salt form of cefamandole formyl ester. Cefamandole nafate is a pro-drug that is hydrolyzed by plasma esterases to produce cefamandole, a semi-synthetic beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. | ||
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