Sotrastaurin
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CAS No. | 425637-18-9 | Cat. No. | BCP07456 |
Name | Sotrastaurin | ||
Synonyms | AEB071; AEB 071; AEB-071; | ||
SMILES | |||
Chemical Name | |||
Formula | C25H22N6O2 | M. Wt | 438.48 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Sotrastaurin, a first-in-class protein kinase C (PKC) inhibitor, is aiming to become the first oral treatment that inhibits T-cell activation since the introduction of calcineurin inhibitors. T-cell activation is an early step in autoimmune diseases such as psoriasis and is also essential for the rejection of transplanted organs. Sotrastaurin blocks a pathway critical to T-cell activation and has shown promise in organ transplantation as well as in autoimmune disorders. Sotrastaurin is developed |
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