Y16
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CAS No. | 429653-73-6 | Cat. No. | BCP25513 |
Name | Y16 | ||
Synonyms | RhoA-IN-Y16; Y-16; Y 16; | ||
SMILES | |||
Chemical Name | |||
Formula | C24H20N2O3 | M. Wt | 384.43 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Y16, also known as RhoA-IN-Y16, is a RhoA inhibitor, Y16 blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor, with Rho (Kd = 80 nM). Y16 specifically inhibits LARG catalyzed activation of RhoA and RhoA signaling pathways. Y16 blocks the growth and migration of MCF7 breast cancer cells. |
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