Lasmiditan New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 439239-90-4 | Cat. No. | BCP04734 |
| Name | Lasmiditan | ||
| Synonyms | COL-144; COL144; COL 144; LY573144; LY-573144; LY 573144; | ||
| SMILES | O=C(NC1=NC(C(C2CCN(C)CC2)=O)=CC=C1)C3=C(F)C=C(F)C=C3F | ||
| Chemical Name | |||
| Formula | C19H18F3N3O2 | M. Wt | 377.36 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Lasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2-hour placebo-subtracted headache response of 28.8%, though with frequent reports of dizziness, paresthesias, and vertigo. | ||
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