BIIB 014
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CAS No. | 442908-10-3 | Cat. No. | BCP15984 |
Name | BIIB 014 | ||
Synonyms | BIIB-014;BIIB014;Vipadenant;CEB4520; V-2006; | ||
SMILES | |||
Chemical Name | |||
Formula | C16H15N7O | M. Wt | 321.34 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Vipadenant showed excellent binding affinity for A2A and had modest selectivity against A1 and A2B (Ki = 63 nM), while it showed good selectivity against A3 (Ki = 1005 nM). Vipadenant was able to increase contralateral rotations in 6-OHDA lesioned rats when dosed orally in combination with apomorphine at 3 and 10 mg/kg. |
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