Resibufogenin
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CAS No. | 465-39-4 | Cat. No. | BCP20705 |
Name | Resibufogenin | ||
Synonyms | RBG; Bufotenine; | ||
SMILES | C[C@]([C@@H](C(C=C1)=COC1=O)C2)(CC[C@@]3([H])[C@@]4([H])CC[C@@]5([H])[C@@]3(CC[C@](O)C5)C)[C@@]64[C@@H]2O6 | ||
Chemical Name | |||
Formula | C24H32O4 | M. Wt | 384.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Resibufogenin is a cardiac glycoside first isolated from Bufonis venom that acts as an inhibitor of the Na+/K+-ATPase.It exhibits cardiotonic, vasopressor, and respiratory stimulating actions in both animal and clinical models.Resibufogenin has been used to antagonize the action of marinobufagenin in a rat experimental model of preeclampsia. Resibufogenin is also reported to have antiproliferative effects against cancer cells, inducing cell cycle arrest by suppressing the expression of cyclin D1. |
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