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CAS No. | 480998-12-7 | Cat. No. | BCP07339 |
Name | INNO-206 HCl | ||
Synonyms | MC-DOXHZN hydrochloride;INNO-206 monohydrochloride; INNO206 HCl salt; Aldoxorubicin HCl; | ||
SMILES | |||
Chemical Name | |||
Formula | C37H42N4O13.HCl | M. Wt | 787.21 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Aldoxorubicin, also known as INNO-206, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. Following intravenous administration, doxorubicin prodrug INNO-206 binds selectively to the cysteine-34 position of albumin via its maleimide moiety. Doxorubicin is released from the albumin carrier after cleavage of the acid-sensitive hydrazone linker within the acidic environment of tumors and, once located intracel |
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