Cinchonidine
Data Sheet
For research use only. Not for human use.
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| CAS No. | 485-71-2 | Cat. No. | BCP18347 |
| Name | Cinchonidine | ||
| Synonyms | Cinchovatine; | ||
| SMILES | O[C@](C1=CC=NC2=C1C=CC=C2)[C@@]3([H])[C@@](CC4)C[C@](C=C)[C@]4([H])C3 | ||
| Chemical Name | |||
| Formula | C19H22N2O | M. Wt | 294.39 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Cinchonidine is an cinchona alkaloid with antimalarial activity. Cinchonidine adsorbed onto a platinum metal catalyst leads to rate acceleration and induces strong stereocontrol in the asymmetric hydrogenation of trifluoroacetophenone. In the hydrogenation of the heteroaromatic ring of cinchonidine in toluene, the diastereomeric excess of the (S)-hexahydrocinchonidine increased upon increasing Pt{111}/Pt{100} ratio, but this distinct shape selectivity was observed only after the oxidative removal of PAA at 473 K. The use of the as-prepared nanoparticles inverted the major diastereomer to R, and this isomer was formed also in acetic acid. | ||
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